Safety, tolerability, and immunogenicity of a novel 4-antigen Staphylococcus aureus vaccine (SA4Ag) in healthy Japanese adults

Safety, tolerability, and immunogenicity of a novel 4-antigen Staphylococcus aureus vaccine (SA4Ag) in healthy Japanese adults

A novel Staphylococcus aureus 4-antigen vaccine (SA4Ag) is under development, comprising capsular polysaccharide serotypes 5 and 8 (CP5 and CP8) conjugated to CRM197, recombinant protein clumping factor A (rmClfA), and recombinant manganese transporter protein C (MntC). We evaluated SA4Ag safety, to...

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Bibliographic Details
Main Authors: Megumi Inoue, Takuma Yonemura, James Baber, Yasuko Shoji, Masakazu Aizawa, David Cooper, Joseph Eiden, William C. Gruber, Kathrin U. Jansen, Annaliesa S. Anderson, Alejandra Gurtman
Format: Article
Language:English
Published: Taylor & Francis Group 2018-11-01
Series:Human Vaccines & Immunotherapeutics
Subjects:
capsular polysaccharide
clumping factor a
functional antibodies
manganese transporter c
staphylococcus aureus
vaccine
Online Access:http://dx.doi.org/10.1080/21645515.2018.1496764

Internet

http://dx.doi.org/10.1080/21645515.2018.1496764

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