RUNX1 regulates site specificity of DNA demethylation by recruitment of DNA demethylation machineries in hematopoietic cells

RUNX1 regulates site specificity of DNA demethylation by recruitment of DNA demethylation machineries in hematopoietic cells

Abstract: RUNX1 is an essential master transcription factor in hematopoietic development and plays important roles in immune functions. Although the gene regulatory mechanism of RUNX1 has been characterized extensively, the epigenetic role of RUNX1 remains unclear. Here, we demonstrate that RUNX1 co...

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Bibliographic Details
Main Authors: Takahiro Suzuki, Yuri Shimizu, Erina Furuhata, Shiori Maeda, Mami Kishima, Hajime Nishimura, Saaya Enomoto, Yoshihide Hayashizaki, Harukazu Suzuki
Format: Article
Language:English
Published: Elsevier 2017-09-01
Series:Blood Advances
Online Access:http://www.sciencedirect.com/science/article/pii/S2473952920303116

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http://www.sciencedirect.com/science/article/pii/S2473952920303116

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