E-Cadherin in Pancreatic Ductal Adenocarcinoma: A Multifaceted Actor during EMT

Epithelial-to-mesenchymal transition (EMT) is a step-wise process observed in normal and tumor cells leading to a switch from epithelial to mesenchymal phenotype. In tumors, EMT provides cancer cells with a metastatic phenotype characterized by E-cadherin down-regulation, cytoskeleton reorganization...

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Bibliographic Details
Main Authors: Michele Sommariva, Nicoletta Gagliano
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/9/4/1040