Role of distinct fibroblast lineages and immune cells in dermal repair following UV radiation-induced tissue damage

Role of distinct fibroblast lineages and immune cells in dermal repair following UV radiation-induced tissue damage

Solar ultraviolet radiation (UVR) is a major source of skin damage, resulting in inflammation, premature ageing, and cancer. While several UVR-induced changes, including extracellular matrix reorganisation and epidermal DNA damage, have been documented, the role of different fibroblast lineages and...

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Bibliographic Details
Main Authors: Emanuel Rognoni, Georgina Goss, Toru Hiratsuka, Kalle H Sipilä, Thomas Kirk, Katharina I Kober, Prudence PokWai Lui, Victoria SK Tsang, Nathan J Hawkshaw, Suzanne M Pilkington, Inchul Cho, Niwa Ali, Lesley E Rhodes, Fiona M Watt
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-12-01
Series:eLife
Subjects:
UVR tissue damage
fibroblast heterogeneity
T cells
COX-2 inhibition
in vivo live imaging
lineage tracing
Online Access:https://elifesciences.org/articles/71052

Internet

https://elifesciences.org/articles/71052

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