Synthesis of Amino Acids Bearing Halodifluoromethyl Moieties and Their Application to p53-Derived Peptides Binding to Mdm2/Mdm4

Synthesis of Amino Acids Bearing Halodifluoromethyl Moieties and Their Application to p53-Derived Peptides Binding to Mdm2/Mdm4

Sebastian Vaas,1 Markus O Zimmermann,1 Theresa Klett,1 Frank M Boeckler1,2 1Department of Pharmacy and Biochemistry, Eberhard Karls Universität Tübingen, Laboratory for Molecular Design and Pharmaceutical Biophysics, Institute of Pharmaceutical Sciences, Tübingen, 72076, Germany; 2Institute for Bioi...

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Bibliographic Details
Main Authors: Vaas S, Zimmermann MO, Klett T, Boeckler FM
Format: Article
Language:English
Published: Dove Medical Press 2023-04-01
Series:Drug Design, Development and Therapy
Subjects:
halogen bonding
solid-phase peptide synthesis
unnatural amino acids
fluorescence polarization assay
oncological target
mdmx
Online Access:https://www.dovepress.com/synthesis-of-amino-acids-bearing-halodifluoromethyl-moieties-and-their-peer-reviewed-fulltext-article-DDDT

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https://www.dovepress.com/synthesis-of-amino-acids-bearing-halodifluoromethyl-moieties-and-their-peer-reviewed-fulltext-article-DDDT

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