Active Immunization with Extracellular Vesicles Derived from Staphylococcus aureus Effectively Protects against Staphylococcal Lung Infections, Mainly via Th1 Cell-Mediated Immunity.

Staphylococcus aureus is an important pathogenic bacterium that causes various infectious diseases. Extracellular vesicles (EVs) released from S. aureus contain bacterial proteins, nucleic acids, and lipids. These EVs can induce immune responses leading to similar symptoms as during staphylococcal i...

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Bibliographic Details
Main Authors: Seng Jin Choi, Min-Hye Kim, Jinseong Jeon, Oh Youn Kim, Youngwoo Choi, Jihye Seo, Sung-Wook Hong, Won-Hee Lee, Seong Gyu Jeon, Yong Song Gho, Young-Koo Jee, Yoon-Keun Kim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4558092?pdf=render