FOXM1 induces a global methylation signature that mimics the cancer epigenome in head and neck squamous cell carcinoma.

FOXM1 induces a global methylation signature that mimics the cancer epigenome in head and neck squamous cell carcinoma.

The oncogene FOXM1 has been implicated in all major types of human cancer. We recently showed that aberrant FOXM1 expression causes stem cell compartment expansion resulting in the initiation of hyperplasia. We have previously shown that FOXM1 regulates HELLS, a SNF2/helicase involved in DNA methyla...

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Bibliographic Details
Main Authors: Muy-Teck Teh, Emilios Gemenetzidis, Deeviyaben Patel, Rameez Tariq, Ayesha Nadir, Adiam W Bahta, Ahmad Waseem, Iain L Hutchison
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3312909?pdf=render

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http://europepmc.org/articles/PMC3312909?pdf=render

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