Discovery of the Elusive UDP-Diacylglucosamine Hydrolase in the Lipid A Biosynthetic Pathway in <named-content content-type="genus-species">Chlamydia trachomatis</named-content>

ABSTRACT Constitutive biosynthesis of lipid A via the Raetz pathway is essential for the viability and fitness of Gram-negative bacteria, including Chlamydia trachomatis. Although nearly all of the enzymes in the lipid A biosynthetic pathway are highly conserved across Gram-negative bacteria, the cl...

Full description

Bibliographic Details
Main Authors: Hayley E. Young, Jinshi Zhao, Jeffrey R. Barker, Ziqiang Guan, Raphael H. Valdivia, Pei Zhou
Format: Article
Language:English
Published: American Society for Microbiology 2016-05-01
Series:mBio
Online Access:https://journals.asm.org/doi/10.1128/mBio.00090-16