NFκB signaling in alveolar rhabdomyosarcoma

Alveolar rhabdomyosarcoma (aRMS) is a pediatric soft tissue cancer commonly associated with a chromosomal translocation that leads to the expression of a Pax3:Foxo1 or Pax7:Foxo1 fusion protein, the developmental underpinnings of which may give clues to its therapeutic approaches. In aRMS, the NFκB–...

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Bibliographic Details
Main Authors: Megan M. Cleary, Atiya Mansoor, Teagan Settelmeyer, Yuichi Ijiri, Katherine J. Ladner, Matthew N. Svalina, Brian P. Rubin, Denis C. Guttridge, Charles Keller
Format: Article
Language:English
Published: The Company of Biologists 2017-09-01
Series:Disease Models & Mechanisms
Subjects:
Online Access:http://dmm.biologists.org/content/10/9/1109