Colorectal Cancer Stem Cell States Uncovered by Simultaneous Single‐Cell Analysis of Transcriptome and Telomeres

Colorectal Cancer Stem Cell States Uncovered by Simultaneous Single‐Cell Analysis of Transcriptome and Telomeres

Abstract Cancer stem cells (CSCs) presumably contribute to tumor progression and drug resistance, yet their definitive features have remained elusive. Here, simultaneous measurement of telomere length and transcriptome in the same cells enables systematic assessment of CSCs in primary colorectal can...

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Bibliographic Details
Main Authors: Hua Wang, Peng Gong, Tong Chen, Shan Gao, Zhenfeng Wu, Xiaodong Wang, Jie Li, Sadie L. Marjani, José Costa, Sherman M. Weissman, Feng Qi, Xinghua Pan, Lin Liu
Format: Article
Language:English
Published: Wiley 2021-04-01
Series:Advanced Science
Subjects:
cancer stem cells
colorectal cancer
epithelial cells
heterogeneity
single‐cell RNA‐seq
telomere length
Online Access:https://doi.org/10.1002/advs.202004320

Internet

https://doi.org/10.1002/advs.202004320

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