Inflammatory Reaction Induced by Two Metalloproteinases Isolated from <i>Bothrops atrox</i> Venom and by Fragments Generated from the Hydrolysis of Basement Membrane Components

Inflammatory Reaction Induced by Two Metalloproteinases Isolated from <i>Bothrops atrox</i> Venom and by Fragments Generated from the Hydrolysis of Basement Membrane Components

Snake venom metalloproteinases (SVMPs) play an important role in local tissue damage of snakebite patients, mostly by hydrolysis of basement membrane (BM) components. We evaluated the proinflammatory activity of SVMPs Atroxlysin-Ia (ATXL) and Batroxrhagin (BATXH) from <i>Bothrops atrox</i&g...

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Bibliographic Details
Main Authors: Michelle Teixeira de Almeida, Luciana Aparecida Freitas-de-Sousa, Monica Colombini, Sarah N. C. Gimenes, Eduardo S. Kitano, Eliana L. Faquim-Mauro, Solange M. T. Serrano, Ana Maria Moura-da-Silva
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Toxins
Subjects:
<i>bothrops atrox</i>
svmps
metalloproteinases
basal membrane
hydrolysis
peptides
inflammation
Online Access:https://www.mdpi.com/2072-6651/12/2/96

Internet

https://www.mdpi.com/2072-6651/12/2/96

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