Wnt proteins can direct planar cell polarity in vertebrate ectoderm

The coordinated orientation of cells across the tissue plane, known as planar cell polarity (PCP), is manifested by the segregation of core PCP proteins to different sides of the cell. Secreted Wnt ligands are involved in many PCP-dependent processes, yet whether they act as polarity cues has been c...

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Bibliographic Details
Main Authors: Chih-Wen Chu, Sergei Y Sokol
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-09-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/16463