Proresolution lipid mediators in multiple sclerosis - differential, disease severity-dependent synthesis - a clinical pilot trial.

The severity and longevity of inflammation is controlled by endogenous counter-regulatory signals. Among them are long-chain polyunsaturated fatty acid (PUFA)-derived lipid mediators, which promote the resolution of inflammation, an active process for returning to tissue homeostasis.To determine whe...

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Bibliographic Details
Main Authors: Harald Prüss, Berit Rosche, Aaron B Sullivan, Benedikt Brommer, Oliver Wengert, Karsten Gronert, Jan M Schwab
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3568070?pdf=render