PUPIL enables mapping and stamping of transient electrical connectivity in developing nervous systems

Summary: Currently, many genetic methods are available for mapping chemical connectivity, but analogous methods for electrical synapses are lacking. Here, we present pupylation-based interaction labeling (PUPIL), a genetically encoded system for noninvasively mapping and stamping transient electrica...

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Bibliographic Details
Main Authors: Shu Xie, Haixiang Li, Fenyong Yao, Jiechang Huang, Xiaomei Yang, Xin Chen, Qiang Liu, Min Zhuang, Shuijin He
Format: Article
Language:English
Published: Elsevier 2021-10-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124721013206