Developing methods to study conformational changes in RNA crystals using a photocaged ligand
Crystallographic observation of structural changes in real time requires that those changes be uniform both spatially and temporally. A primary challenge with time-resolved ligand-mixing diffraction experiments is asynchrony caused by variable factors, such as efficiency of mixing, rate of diffusion...
| Main Authors: | , , , , , , , , |
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| 格式: | 文件 |
| 语言: | English |
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Frontiers Media S.A.
2022-08-01
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| 丛编: | Frontiers in Molecular Biosciences |
| 主题: | |
| 在线阅读: | https://www.frontiersin.org/articles/10.3389/fmolb.2022.964595/full |