Spatial expression of the FGFR2b splice isoform and its prognostic significance in endometrioid endometrial carcinoma

Spatial expression of the FGFR2b splice isoform and its prognostic significance in endometrioid endometrial carcinoma

Abstract Endometrial carcinoma (EC) is the most common gynecological malignancy and fibroblast growth factor receptor 2 (FGFR2) is a frequently dysregulated receptor tyrosine kinase. FGFR2b and FGFR2c are the two main splice isoforms of FGFR2 and are normally localized in epithelial and mesenchymal...

Full description

Bibliographic Details
Main Authors: Asmerom T Sengal, Deborah Smith, Cameron E Snell, Samuel Leung, Aline Talhouk, Elizabeth D Williams, Jessica N McAlpine, Pamela M Pollock
Format: Article
Language:English
Published: Wiley 2022-11-01
Series:The Journal of Pathology: Clinical Research
Subjects:
alternative splicing
biomarkers
endometrial carcinoma
uterine cancer
endometrial hyperplasia
FGFR2b isoform
Online Access:https://doi.org/10.1002/cjp2.286

Internet

https://doi.org/10.1002/cjp2.286

Similar Items