Regulating Stem Cell-Related Genes Induces the Plastic Differentiation of Cancer Stem Cells to Treat Breast Cancer

Regulating Stem Cell-Related Genes Induces the Plastic Differentiation of Cancer Stem Cells to Treat Breast Cancer

Relapse of cancer is associated with multidirectional differentiation and unrestricted proliferative replication potential of cancer stem cells. Herein, we propose the plastic differentiation strategy for irreversible differentiation of cancer stem cells; further, salinomycin and its newly construct...

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Bibliographic Details
Main Authors: Jing-Ying Zhang, Qian Luo, Jia-Rui Xu, Jing Bai, Li-Min Mu, Yan Yan, Jia-Lun Duan, Yi-Nuo Cui, Zhan-Bo Su, Ying Xie, Wan-Liang Lu
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:Molecular Therapy: Oncolytics
Subjects:
cancer stem cells
plastic differentiation
salinomycin
stem cell-related genes
PKC α signaling pathway
Online Access:http://www.sciencedirect.com/science/article/pii/S2372770520301133

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http://www.sciencedirect.com/science/article/pii/S2372770520301133

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