Activation of protein kinase A and exchange protein directly activated by cAMP promotes adipocyte differentiation of human mesenchymal stem cells.

Activation of protein kinase A and exchange protein directly activated by cAMP promotes adipocyte differentiation of human mesenchymal stem cells.

Human mesenchymal stem cells are primary multipotent cells capable of differentiating into several cell types including adipocytes when cultured under defined in vitro conditions. In the present study we investigated the role of cAMP signaling and its downstream effectors, protein kinase A (PKA) and...

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Bibliographic Details
Main Authors: Bingbing Jia, Lise Madsen, Rasmus Koefoed Petersen, Nathalie Techer, Reidun Kopperud, Tao Ma, Stein Ove Døskeland, Gérard Ailhaud, Jinfu Wang, Ez-Zoubir Amri, Karsten Kristiansen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3313974?pdf=render

Internet

http://europepmc.org/articles/PMC3313974?pdf=render

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