Inorganic phosphate accelerates the migration of vascular smooth muscle cells: evidence for the involvement of miR-223.

BACKGROUND: An elevated serum inorganic phosphate (Pi) level is a major risk factor for kidney disease and downstream vascular complications. We focused on the effect of Pi levels on human aortic vascular smooth muscle cells (VSMCs), with an emphasis on the role of microRNAs (miRNAs). METHODOLOGY/PR...

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Bibliographic Details
Main Authors: Ashraf Yusuf Rangrez, Eléonore M'Baya-Moutoula, Valérie Metzinger-Le Meuth, Lucie Hénaut, Mohamed Seif el Islam Djelouat, Joyce Benchitrit, Ziad A Massy, Laurent Metzinger
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3475714?pdf=render