Aluminium Binding to Modified Amyloid-β Peptides: Implications for Alzheimer’s Disease

Aluminium Binding to Modified Amyloid-β Peptides: Implications for Alzheimer’s Disease

Aluminium (Al) is clearly neurotoxic and considerable evidence exists that Al may play a role in the aetiology or pathogenesis of Alzheimer’s disease (AD). Nevertheless, the link between AD pathology and Al is still open to debate. Therefore, we investigated here the interaction of aluminium ions wi...

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Bibliographic Details
Main Authors: Cosmin Stefan Mocanu, Monica Jureschi, Gabi Drochioiu
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Molecules
Subjects:
amyloid-β peptides
modified Aβ peptide fragments
aluminium ions
metal binding
mass spectrometry
circular dichroism spectroscopy
Online Access:https://www.mdpi.com/1420-3049/25/19/4536

Internet

https://www.mdpi.com/1420-3049/25/19/4536

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