Bmpr2 mutant mice are an inadequate model for studying iron deficiency in pulmonary hypertension
Abstract As bone morphogenetic protein receptor type II (Bmpr2) mutations are the most common genetic cause of pulmonary arterial hypertension (PAH), and iron deficiency (ID) is associated with worse clinical outcomes in PAH patients, we proposed to use Bmpr2 ± mice to induce a model of ID in pulmon...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2022-10-01
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Series: | Pulmonary Circulation |
Subjects: | |
Online Access: | https://doi.org/10.1002/pul2.12151 |