Changes in retinal function and morphology are early clinical signs of disease in cattle with bovine spongiform encephalopathy.

Bovine spongiform encephalopathy (BSE) belongs to a group of fatal, transmissible protein misfolding diseases known as transmissible spongiform encephalopathies (TSEs). All TSEs are caused by accumulation of misfolded prion protein (PrPSc) throughout the central nervous system (CNS), which results i...

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Bibliographic Details
Main Authors: M Heather West Greenlee, Jodi D Smith, Ekundayo M Platt, Jessica R Juarez, Leo L Timms, Justin J Greenlee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4355414?pdf=render