GSDMD in peripheral myeloid cells regulates microglial immune training and neuroinflammation in Parkinson's disease

GSDMD in peripheral myeloid cells regulates microglial immune training and neuroinflammation in Parkinson's disease

Peripheral bacterial infections without impaired blood–brain barrier integrity have been attributed to the pathogenesis of Parkinson's disease (PD). Peripheral infection promotes innate immune training in microglia and exacerbates neuroinflammation. However, how changes in the peripheral enviro...

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Bibliographic Details
Main Authors: Bingwei Wang, Yan Ma, Sheng Li, Hang Yao, Mingna Gu, Ying Liu, You Xue, Jianhua Ding, Chunmei Ma, Shuo Yang, Gang Hu
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Parkinson's disease
Neuroinflammation
Immune training
GSDMD
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383523001247

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http://www.sciencedirect.com/science/article/pii/S2211383523001247

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