hERG1 and HIF-2α Behave as Biomarkers of Positive Response to Bevacizumab in Metastatic Colorectal Cancer Patients

hERG1 and HIF-2α Behave as Biomarkers of Positive Response to Bevacizumab in Metastatic Colorectal Cancer Patients

Background: In search of novel biomarkers of response to bevacizumab in metastatic colorectal cancer (mCRC), we analyzed the expression and prognostic role of several proteins related to angiogenesis. Methods: A retrospective, multicenter study on 80 surgical samples from mCRC patients treated in fi...

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Bibliographic Details
Main Authors: Jessica Iorio, Elena Lastraioli, Lorenzo Tofani, Giulia Petroni, Lorenzo Antonuzzo, Luca Messerini, Giuseppe Perrone, Damiano Caputo, Maria Francesconi, Maria Michelina Amato, Moris Cadei, Giuseppina Arcangeli, Vincenzo Villanacci, Luca Boni, Roberto Coppola, Francesco Di Costanzo, Annarosa Arcangeli
Format: Article
Language:English
Published: Elsevier 2020-03-01
Series:Translational Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523319303766

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http://www.sciencedirect.com/science/article/pii/S1936523319303766

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