Carboxyl Terminus of Hsp70-Interacting Protein Is Increased in Serum and Cerebrospinal Fluid of Patients With Spinocerebellar Ataxia Type 3

Carboxyl Terminus of Hsp70-Interacting Protein Is Increased in Serum and Cerebrospinal Fluid of Patients With Spinocerebellar Ataxia Type 3

Background: Spinocerebellar ataxia type 3 (SCA3)/Machado-Joseph disease (MJD) is the most common type of autosomal dominant ataxia. Like other neurodegenerative diseases, is characterized by the dysfunction of the protein quality control (PQC) system. The carboxyl terminus of the Hsp70-interacting p...

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Bibliographic Details
Main Authors: Zheng-wei Hu, Zhi-hua Yang, Shuo Zhang, Yu-tao Liu, Jing Yang, Yan-lin Wang, Cheng-yuan Mao, Qi-meng Zhang, Chang-he Shi, Yu-ming Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Neurology
Subjects:
CHIP
SCA3
serum
cerebrospinal fluid
SARA
ICARS
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2019.01094/full

Internet

https://www.frontiersin.org/article/10.3389/fneur.2019.01094/full

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