Cystathionine gamma-lyase (CTH) inhibition attenuates glioblastoma formation

Cystathionine gamma-lyase (CTH) inhibition attenuates glioblastoma formation

Purpose: Glioblastoma (GBM) is the most common type of adult brain tumor with extremely poor survival. Cystathionine-gamma lyase (CTH) is one of the main Hydrogen Sulfide (H2S) producing enzymes and its expression contributes to tumorigenesis and angiogenesis but its role in glioblastoma development...

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Bibliographic Details
Main Authors: Maria Peleli, Ivi Antoniadou, Dorival Mendes Rodrigues-Junior, Odysseia Savvoulidou, Laia Caja, Antonia Katsouda, Daniel F.J. Ketelhuth, Jane Stubbe, Kirsten Madsen, Aristidis Moustakas, Andreas Papapetropoulos
Format: Article
Language:English
Published: Elsevier 2023-08-01
Series:Redox Biology
Subjects:
Cystathionine gamma-lyase (CTH)
Glioblastoma stem cells (GSC)
Brain blood vessels
Sex determining region Y-Box 2 (SOX2)
Online Access:http://www.sciencedirect.com/science/article/pii/S221323172300174X

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http://www.sciencedirect.com/science/article/pii/S221323172300174X

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