Nuclear import of PTPN18 inhibits breast cancer metastasis mediated by MVP and importin β2

Abstract Distant metastasis is the primary cause of breast cancer-associated death. The existing information, such as the precise molecular mechanisms and effective therapeutic strategies targeting metastasis, is insufficient to combat breast cancer. This study demonstrates that the protein tyrosine...

Full description

Bibliographic Details
Main Authors: Tao Wang, Xinlei Ba, Xiaonan Zhang, Na Zhang, Guowen Wang, Bin Bai, Tong Li, Jiahui Zhao, Yanjiao Zhao, Yang Yu, Bing Wang
Format: Article
Language:English
Published: Nature Publishing Group 2022-08-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-022-05167-z