GRHL2 regulates keratinocyte EMT-MET dynamics and scar formation during cutaneous wound healing

Abstract After cutaneous wounds successfully heal, keratinocytes that underwent the epithelial-mesenchymal transition (EMT) regain their epithelial characteristics, while in scar tissue, epidermal cells persist in a mesenchymal state. However, the regulatory mechanisms governing this reversion are p...

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Bibliographic Details
Main Authors: Tianying Chen, Bo Zhang, Hanqi Xie, Chenyu Huang, Qiong Wu
Format: Article
Language:English
Published: Nature Publishing Group 2024-10-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-024-07121-7