Androgen receptor signaling–mitochondrial DNA–oxidative phosphorylation: A critical triangle in early prostate cancer

Abstract. Mitochondria are more than just the cellular powerhouse. They also play key roles in vital functions such as apoptosis, metabolism regulation, and other intracellular interactions. The mitochondrial DNA (mtDNA) encodes for 12 subunits of the oxidative phosphorylation (OXPHOS) system. Deple...

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Bibliographic Details
Main Authors: Minas Sakellakis, Laura Jacqueline Flores
Format: Article
Language:English
Published: Wolters Kluwer Health 2022-12-01
Series:Current Urology
Online Access:http://journals.lww.com/10.1097/CU9.0000000000000120