Androgen receptor signaling–mitochondrial DNA–oxidative phosphorylation: A critical triangle in early prostate cancer
Abstract. Mitochondria are more than just the cellular powerhouse. They also play key roles in vital functions such as apoptosis, metabolism regulation, and other intracellular interactions. The mitochondrial DNA (mtDNA) encodes for 12 subunits of the oxidative phosphorylation (OXPHOS) system. Deple...
Main Authors: | Minas Sakellakis, Laura Jacqueline Flores |
---|---|
Format: | Article |
Language: | English |
Published: |
Wolters Kluwer Health
2022-12-01
|
Series: | Current Urology |
Online Access: | http://journals.lww.com/10.1097/CU9.0000000000000120 |
Similar Items
-
Niclosamide in prostate cancer: An inhibitor of AR-V7, a mitochondrial uncoupler, or more?
by: Minas Sakellakis
Published: (2023-01-01) -
Proteomic and Transcriptomic Profiling Reveals Mitochondrial Oxidative Phosphorylation as Therapeutic Vulnerability in Androgen Receptor Pathway Active Prostate Tumors
by: Caroline Xue, et al.
Published: (2022-03-01) -
Androgen Receptor Signaling in Prostate Cancer Genomic Subtypes
by: Mohamed Ali Hussein, et al.
Published: (2023-10-01) -
Androgen Receptor Signaling in Prostate Cancer Genomic Subtypes
by: Lauren K. Jillson, et al.
Published: (2021-06-01) -
Androgen Receptor Signaling in Prostate Cancer and Therapeutic Strategies
by: Aasems Jacob, et al.
Published: (2021-10-01)