Cholera Toxin Encapsulated within Several <i>Vibrio cholerae</i> O1 Serotype Inaba Outer Membrane Vesicles Lacks a Functional B-Subunit

Cholera toxin (CT), the major virulence factor of <i>Vibrio cholerae</i>, is an AB5 toxin secreted through the type II secretion system (T2SS). Upon secretion, the toxin initiates endocytosis through the interaction of the B pentamer with the GM1 ganglioside receptor on small intestinal...

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Bibliographic Details
Main Authors: Elnaz S. Rasti, Angela C. Brown
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:Toxins
Subjects:
Online Access:https://www.mdpi.com/2072-6651/11/4/207