APPswe/PS1dE9 mice with cortical amyloid pathology show a reduced NAA/Cr ratio without apparent brain atrophy: A MRS and MRI study

APPswe/PS1dE9 mice with cortical amyloid pathology show a reduced NAA/Cr ratio without apparent brain atrophy: A MRS and MRI study

Transgenic animal models of Aβ pathology provide mechanistic insight into some aspects of Alzheimer disease (AD) pathology related to Aβ accumulation. Quantitative neuroimaging is a possible aid to improve translation of mechanistic findings in transgenic models to human end phenotypes of brain morp...

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Bibliographic Details
Main Authors: Angela Kuhla, Claire Rühlmann, Tobias Lindner, Stefan Polei, Stefan Hadlich, Bernd J. Krause, Brigitte Vollmar, Stefan J. Teipel
Format: Article
Language:English
Published: Elsevier 2017-01-01
Series:NeuroImage: Clinical
Online Access:http://www.sciencedirect.com/science/article/pii/S2213158217301407

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http://www.sciencedirect.com/science/article/pii/S2213158217301407

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