Identification of early biomarkers during acetaminophen-induced hepatotoxicity by fourier transform infrared microspectroscopy.

Acetaminophen is a widely prescribed drug used to relieve pain and fever; however, it is a leading cause of drug-induced liver injury and a burden on public healthcare. In this study, hepatotoxicity in mice post oral dosing of acetaminophen was investigated using liver and sera samples with Fourier...

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Bibliographic Details
Main Authors: Rekha Gautam, Bhagawat Chandrasekar, Mukta Deobagkar-Lele, Srabanti Rakshit, Vinay Kumar B N, Siva Umapathy, Dipankar Nandi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3446881?pdf=render