A chromosomally encoded virulence factor protects the Lyme disease pathogen against host-adaptive immunity.

Borrelia burgdorferi, the bacterial pathogen of Lyme borreliosis, differentially expresses select genes in vivo, likely contributing to microbial persistence and disease. Expression analysis of spirochete genes encoding potential membrane proteins showed that surface-located membrane protein 1 (lmp1...

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Bibliographic Details
Main Authors: Xiuli Yang, Adam S Coleman, Juan Anguita, Utpal Pal
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-03-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2644780?pdf=render