Tolerable treatment of glioblastoma with redox-cycling ‘mitocans': a comparative study in vivo

ABSTRACTObjectives: The present study describes a pharmacological strategy for the treatment of glioblastoma by redoxcycling ‘mitocans’ such as quinone/ascorbate combination drugs, based on their tumor-selective redox-modulating effects and tolerance to normal cells and tissues.Methods: Experiments...

Full description

Bibliographic Details
Main Authors: Akira Sumiyoshi, Sayaka Shibata, Dessislava Lazarova, Zhivko Zhelev, Ichio Aoki, Rumiana Bakalova
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Redox Report
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/13510002.2023.2220531