The mouse retinal pigment epithelium mounts an innate immune defense response following retinal detachment

Abstract The retinal pigment epithelium (RPE) maintains photoreceptor viability and function, completes the visual cycle, and forms the outer blood-retinal barrier (oBRB). Loss of RPE function gives rise to several monogenic retinal dystrophies and contributes to age-related macular degeneration. Re...

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Bibliographic Details
Main Authors: Steven F. Abcouwer, Bruna Miglioranza Scavuzzi, Phillip E. Kish, Dejuan Kong, Sumathi Shanmugam, Xuan An Le, Jingyu Yao, Heather Hager, David N Zacks
Format: Article
Language:English
Published: BMC 2024-03-01
Series:Journal of Neuroinflammation
Online Access:https://doi.org/10.1186/s12974-024-03062-2