Single-cell RNA-seq analysis unveils a prevalent epithelial/mesenchymal hybrid state during mouse organogenesis

Single-cell RNA-seq analysis unveils a prevalent epithelial/mesenchymal hybrid state during mouse organogenesis

Abstract Background Organogenesis is crucial for proper organ formation during mammalian embryonic development. However, the similarities and shared features between different organs and the cellular heterogeneity during this process at single-cell resolution remain elusive. Results We perform singl...

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Bibliographic Details
Main Authors: Ji Dong, Yuqiong Hu, Xiaoying Fan, Xinglong Wu, Yunuo Mao, Boqiang Hu, Hongshan Guo, Lu Wen, Fuchou Tang
Format: Article
Language:English
Published: BMC 2018-03-01
Series:Genome Biology
Subjects:
Single-cell RNA-seq
Organogenesis
Interactions between mesenchyme and epithelium
Epithelial/mesenchymal hybrid state
Online Access:http://link.springer.com/article/10.1186/s13059-018-1416-2

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http://link.springer.com/article/10.1186/s13059-018-1416-2

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