Complement-related proteins control the flavivirus infection of Aedes aegypti by inducing antimicrobial peptides.

The complement system functions during the early phase of infection and directly mediates pathogen elimination. The recent identification of complement-like factors in arthropods indicates that this system shares common ancestry in vertebrates and invertebrates as an immune defense mechanism. Thioes...

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Bibliographic Details
Main Authors: Xiaoping Xiao, Yang Liu, Xiaoyan Zhang, Jing Wang, Zuofeng Li, Xiaojing Pang, Penghua Wang, Gong Cheng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-04-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3983052?pdf=render