Challenges in, and recommendations for, hyperspectral imaging in ex vivo malignant glioma biopsy measurements

Abstract The visualization of protoporphyrin IX (PPIX) fluorescence with the help of surgical microscopes during 5-aminolevulinic acid-mediated fluorescence-guided resection (FGR) of gliomas is still limited at the tumor margins. Hyperspectral imaging (HI) detects PPIX more sensitively but is not ye...

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Bibliographic Details
Main Authors: Anna Walke, David Black, Pablo A. Valdes, Walter Stummer, Simone König, Eric Suero-Molina
Format: Article
Language:English
Published: Nature Portfolio 2023-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-30680-2