Identification of a PEST Sequence in Vertebrate KIR2.1 That Modifies Rectification

Identification of a PEST Sequence in Vertebrate KIR2.1 That Modifies Rectification

KIR2.1 potassium channels, producing inward rectifier potassium current (IK1), are important for final action potential repolarization and a stable resting membrane potential in excitable cells like cardiomyocytes. Abnormal KIR2.1 function, either decreased or increased, associates with diseases suc...

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Bibliographic Details
Main Authors: Muge Qile, Yuan Ji, Marien J. C. Houtman, Marlieke Veldhuis, Fee Romunde, Bart Kok, Marcel A. G. van der Heyden
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Physiology
Subjects:
KIR2.1
inward rectifier
PEST domain
vertebrates
patch clamp
potassium
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2019.00863/full

Internet

https://www.frontiersin.org/article/10.3389/fphys.2019.00863/full

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