SARS-CoV-2 ORF3c impairs mitochondrial respiratory metabolism, oxidative stress, and autophagic flux

SARS-CoV-2 ORF3c impairs mitochondrial respiratory metabolism, oxidative stress, and autophagic flux

Summary: Coronaviruses encode a variable number of accessory proteins that are involved in host-virus interaction, suppression of immune responses, or immune evasion. SARS-CoV-2 encodes at least twelve accessory proteins, whose roles during infection have been studied. Nevertheless, the role of the...

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Bibliographic Details
Main Authors: Alessandra Mozzi, Monica Oldani, Matilde E. Forcella, Chiara Vantaggiato, Gioia Cappelletti, Chiara Pontremoli, Francesca Valenti, Diego Forni, Marina Saresella, Mara Biasin, Manuela Sironi, Paola Fusi, Rachele Cagliani
Format: Article
Language:English
Published: Elsevier 2023-07-01
Series:iScience
Subjects:
Virology
Cell biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223011951

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http://www.sciencedirect.com/science/article/pii/S2589004223011951

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