Adiponectin Inhibits the Production of TNF-α, IL-6 and Chemokines by Human Lung Macrophages

Adiponectin Inhibits the Production of TNF-α, IL-6 and Chemokines by Human Lung Macrophages

Background: Obesity is associated with an elevated risk of severe respiratory infections and inflammatory lung diseases. The objectives were to investigate 1) the production of adiponectin by human lung explants, 2) the expression of the adiponectin receptors AdipoR1 and AdipoR2 by human lung macrop...

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Bibliographic Details
Main Authors: Hélène Salvator, Stanislas Grassin-Delyle, Marion Brollo, Louis-Jean Couderc, Charlotte Abrial, Tatiana Victoni, Emmanuel Naline, Philippe Devillier
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Pharmacology
Subjects:
adiponectin
obesity
human lung macrophage
cytokine
adiporon
LPS
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.718929/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.718929/full

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