Live imaging-based model selection reveals periodic regulation of the stochastic G1/S phase transition in vertebrate axial development.
In multicellular organism development, a stochastic cellular response is observed, even when a population of cells is exposed to the same environmental conditions. Retrieving the spatiotemporal regulatory mode hidden in the heterogeneous cellular behavior is a challenging task. The G1/S transition o...
Main Authors: | , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-12-01
|
Series: | PLoS Computational Biology |
Online Access: | http://europepmc.org/articles/PMC4256085?pdf=render |