Schistosoma japonicum Cystatin Alleviates Sepsis Through Activating Regulatory Macrophages

Schistosoma japonicum Cystatin Alleviates Sepsis Through Activating Regulatory Macrophages

Multi-organ failure caused by the inflammatory cytokine storm induced by severe infection is the major cause of death for sepsis. Sj-Cys is a cysteine protease inhibitor secreted by Schistosoma japonicum with strong immunomodulatory functions on host immune system. Our previous studies have shown th...

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Bibliographic Details
Main Authors: Hong Xie, Lingqin Wu, Xingzhi Chen, Shifang Gao, Huihui Li, Yuan Yuan, Jinbao Liang, Xiaoli Wang, Shuying Wang, Changyan Xu, Liang Chu, Bin Zhan, Rui Zhou, Xiaodi Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
cysteine protease inhibitor
Schistosoma japonicum
sepsis
macrophage
immunomodulation
adoptive transfer
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2021.617461/full

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https://www.frontiersin.org/articles/10.3389/fcimb.2021.617461/full

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