Flavonoid Derivatives as New Potent Inhibitors of Cysteine Proteases: An Important Step toward the Design of New Compounds for the Treatment of Leishmaniasis

Flavonoid Derivatives as New Potent Inhibitors of Cysteine Proteases: An Important Step toward the Design of New Compounds for the Treatment of Leishmaniasis

Leishmaniasis is a neglected tropical disease, affecting more than 350 million people globally. However, there is currently no vaccine available against human leishmaniasis, and current treatment is hampered by high cost, side-effects, and painful administration routes. It has become a United Nation...

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Bibliographic Details
Main Authors: Estela Mariana Guimarães Lourenço, Juliana Fortes Di Iório, Fernanda da Silva, Felipe Leonardo Bley Fialho, Melquisedeque Mateus Monteiro, Adilson Beatriz, Renata Trentin Perdomo, Euzébio Guimarães Barbosa, Jean Pierre Oses, Carla Cardozo Pinto de Arruda, Wagner Alves de Souza Júdice, Jamal Rafique, Dênis Pires de Lima
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Microorganisms
Subjects:
synthesis
leishmaniasis
flavonoids
rCPB
molecular modelling
Online Access:https://www.mdpi.com/2076-2607/11/1/225

Internet

https://www.mdpi.com/2076-2607/11/1/225

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