Preoperative administration of branched-chain amino acids reduces postoperative insulin resistance in rats by reducing liver gluconeogenesis

Preoperative administration of branched-chain amino acids reduces postoperative insulin resistance in rats by reducing liver gluconeogenesis

Abstract Background Postoperative insulin resistance (PIR) represents an important characteristic of metabolic response following surgical injury. Clinical outcomes are negatively correlated to postoperative insulin resistance and hyperglycemia, indicating a novel treatment for reducing postoperativ...

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Bibliographic Details
Main Authors: Jin Zhang, Rui Chi, Yunpeng Zhang, Yi Xie, Yunxia Liu, Qun Bao, Hengyu Lv, Bo Han, Haipeng Sun, Peng Sun
Format: Article
Language:English
Published: BMC 2022-11-01
Series:Nutrition & Metabolism
Subjects:
Branched-chain amino acids
Postoperative insulin resistance
Gluconeogenesis
CRTC2
G6PC
Hyperglycemia
Online Access:https://doi.org/10.1186/s12986-022-00710-3

Internet

https://doi.org/10.1186/s12986-022-00710-3

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