Comparative study of two protocols for quantitative image-analysis of serotonin transporter clustering in lymphocytes, a putative biomarker of therapeutic efficacy in major depression

Comparative study of two protocols for quantitative image-analysis of serotonin transporter clustering in lymphocytes, a putative biomarker of therapeutic efficacy in major depression

Abstract Background The pattern of serotonin transporter clustering on the plasma membrane of lymphocytes extracted from human whole blood samples has been identified as a putative biomarker of therapeutic efficacy in major depression. Here we evaluated the possibility of performing a similar analys...

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Bibliographic Details
Main Authors: Raquel Romay-Tallon, Tania Rivera-Baltanas, Josh Allen, Jose M. Olivares, Lisa E. Kalynchuk, Hector J. Caruncho
Format: Article
Language:English
Published: BMC 2017-09-01
Series:Biomarker Research
Subjects:
Biomarkers
Depression
Blood smears
Serotonin transporter
Lymphocytes
Membrane protein clustering
Online Access:http://link.springer.com/article/10.1186/s40364-017-0107-6

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http://link.springer.com/article/10.1186/s40364-017-0107-6

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