Cilostazol Attenuates AngII-Induced Cardiac Fibrosis in apoE Deficient Mice

Cilostazol Attenuates AngII-Induced Cardiac Fibrosis in apoE Deficient Mice

Cardiac fibrosis is characterized by the net accumulation of extracellular matrix in the myocardium and is an integral component of most pathological cardiac conditions. Cilostazol, a selective inhibitor of phosphodiesterase type III with anti-platelet, anti-mitogenic, and vasodilating properties, i...

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Bibliographic Details
Main Authors: Yoshiko Hada, Haruhito A. Uchida, Ryoko Umebayashi, Masashi Yoshida, Jun Wada
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:International Journal of Molecular Sciences
Subjects:
cilostazol
angiotensin II
fibrosis
osteopontin
cAMP-PKA
Online Access:https://www.mdpi.com/1422-0067/23/16/9065

Internet

https://www.mdpi.com/1422-0067/23/16/9065

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