Bayesian localization of CNV candidates in WGS data within minutes
Abstract Background Full Bayesian inference for detecting copy number variants (CNV) from whole-genome sequencing (WGS) data is still largely infeasible due to computational demands. A recently introduced approach to perform Forward–Backward Gibbs sampling using dynamic Haar wavelet compression has...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2019-09-01
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Series: | Algorithms for Molecular Biology |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13015-019-0154-7 |