The investigation of interaction between Thioguanine and human serum albumin by fluorescence and modeling

The interaction between Thioguanine (6-TG) and human serum albumin (HSA) under simulative physiological conditions was studied using fluorescence spectroscopy in combination with UV absorption and molecular modeling method. A strong fluorescence quenching reaction of 6-TG to HSA was observed and the...

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Bibliographic Details
Main Authors: Xin An, Jiajia Zhao, Fengling Cui, Guirong Qu
Format: Article
Language:English
Published: Elsevier 2017-05-01
Series:Arabian Journal of Chemistry
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1878535213001974